Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Cytochrome b-245 light chain alpha chain (80-160 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CYBA |
Gene ID: |
1535 |
Uniprot ID: |
CY24A_HUMAN |
Immunogen Region: |
80-160 aa |
Specificity: |
CY24A Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 80-160 |
Function | Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. |
Protein Name | Cytochrome B-245 Light ChainCytochrome B(558 Alpha ChainCytochrome B558 Subunit AlphaNeutrophil Cytochrome B 22 Kda PolypeptideSuperoxide-Generating Nadph Oxidase Light Chain SubunitP22 Phagocyte B-CytochromeP22-PhoxP22phox |
Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-1236973Reactome: R-HSA-3299685Reactome: R-HSA-4420097Reactome: R-HSA-5668599Reactome: R-HSA-6798695Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423Reactome: R-HSA-9673324 |
Cellular Localisation | Cell MembraneAs Unassembled Monomer May Localize To The Endoplasmic Reticulum |
Alternative Antibody Names | Anti-Cytochrome B-245 Light Chain antibodyAnti-Cytochrome B(558 Alpha Chain antibodyAnti-Cytochrome B558 Subunit Alpha antibodyAnti-Neutrophil Cytochrome B 22 Kda Polypeptide antibodyAnti-Superoxide-Generating Nadph Oxidase Light Chain Subunit antibodyAnti-P22 Phagocyte B-Cytochrome antibodyAnti-P22-Phox antibodyAnti-P22phox antibodyAnti-CYBA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance