| Host: | Rabbit |
| Applications: | CM/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-CXCR5 (320-370) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.50-1.20 µg/µl |
| Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | CXCR5 |
| Gene ID: | 643 |
| Uniprot ID: | CXCR5_HUMAN |
| Immunogen Region: | 320-370 |
| Immunogen: | Synthetic peptide taken within amino acid region 320-370 on human Chemokine (C-X-C motif) receptor 5 protein. |
| Tissue Specificity | Expression in mature B-cells and Burkitt lymphoma cells. |
| Function | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
| Protein Name | C-X-C Chemokine Receptor Type 5 Cxc-R5 Cxcr-5 Burkitt Lymphoma Receptor 1 Monocyte-Derived Receptor 15 Mdr-15 Cd Antigen Cd185 |
| Database Links | Reactome: R-HSA-380108 Reactome: R-HSA-418594 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 5 antibody Anti-Cxc-R5 antibody Anti-Cxcr-5 antibody Anti-Burkitt Lymphoma Receptor 1 antibody Anti-Monocyte-Derived Receptor 15 antibody Anti-Mdr-15 antibody Anti-Cd Antigen Cd185 antibody Anti-CXCR5 antibody Anti-BLR1 antibody Anti-MDR15 antibody |
Information sourced from Uniprot.org