| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CTNNBL1 |
| Gene ID: | 56259 |
| Uniprot ID: | CTBL1_HUMAN |
| Immunogen Region: | 264-563 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 264-563 of human CTNNBL1 (NP_110517.2). |
| Immunogen Sequence: | EVLAILLQDNDENRELLGEL DGIDVLLQQLSVFKRHNPST AEEQEMMENLFDSLCSCLML SSNRERFLKGEGLQLMNLML REKKISRSSALKVLDHAMIG PEGTDNCHKFVDILGLRTIF PLFMKSPRKIKKVGTTEKEH EEHVCSILASLLRNLRGQQR TRLLNKFTENDSEKVDRLME LHFKYLGAMQVADKKIEGEK HDMVRRGEIIDNDTEEEFYL RRLDAGLFVLQHICYIMAE |
| Tissue Specificity | Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid. |
| Function | Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated somatic hypermutation (SHM) and class-switch recombination (CSR), 2 processes resulting in the production of high-affinity, mutated isotype-switched antibodies. |
| Protein Name | Beta-Catenin-Like Protein 1Nuclear-Associated ProteinNapTestis Development Protein Nyd-Sp19 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Isoform 1: NucleusIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Beta-Catenin-Like Protein 1 antibodyAnti-Nuclear-Associated Protein antibodyAnti-Nap antibodyAnti-Testis Development Protein Nyd-Sp19 antibodyAnti-CTNNBL1 antibodyAnti-C20orf33 antibodyAnti-PP8304 antibody |
Information sourced from Uniprot.org