Anti-CTDNEP1 antibody (100-180 aa) (STJ191388)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 100-180
General Information
| Short Description | Rabbit polyclonal anti-CTD nuclear envelope phosphatase 1 (100-180 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CTDNEP1 |
| Gene ID | 23399 |
| Uniprot ID | CNEP1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 100-180 |
| Immunogen Region | 100-180 aa |
| Specificity | CNEP1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling. |
| Protein Name | Ctd Nuclear Envelope Phosphatase 1Serine/Threonine-Protein Phosphatase Dullard |
| Database Links | Reactome: R-HSA-4419969 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinNucleus Membrane |
| Alternative Antibody Names | Anti-Ctd Nuclear Envelope Phosphatase 1 antibodyAnti-Serine/Threonine-Protein Phosphatase Dullard antibodyAnti-CTDNEP1 antibodyAnti-DULLARD antibody |
Information sourced from Uniprot.org