| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CSTF1 |
| Gene ID: | 1477 |
| Uniprot ID: | CSTF1_HUMAN |
| Immunogen Region: | 1-220 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CSTF1 (NP_001315.1). |
| Immunogen Sequence: | MYRTKVGLKDRQQLYKLIIS QLLYDGYISIANGLINEIKP QSVCAPSEQLLHLIKLGMEN DDTAVQYAIGRSDTVAPGTG IDLEFDADVQTMSPEASEYE TCYVTSHKGPCRVATYSRDG QLIATGSADASIKILDTERM LAKSAMPIEVMMNETAQQNM ENHPVIRTLYDHVDEVTCLA FHPTEQILASGSRDYTLKLF DYSKPSAKRAFKYIQEAEML |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA. |
| Protein Name | Cleavage Stimulation Factor Subunit 1Cf-1 50 Kda SubunitCleavage Stimulation Factor 50 Kda SubunitCstf 50 Kda SubunitCstf-50 |
| Database Links | Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cleavage Stimulation Factor Subunit 1 antibodyAnti-Cf-1 50 Kda Subunit antibodyAnti-Cleavage Stimulation Factor 50 Kda Subunit antibodyAnti-Cstf 50 Kda Subunit antibodyAnti-Cstf-50 antibodyAnti-CSTF1 antibody |
Information sourced from Uniprot.org
