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Anti-CSNK2B antibody (166-215 aa) (STJ92009)

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CKII-beta Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HUVEC cells, using CKII-beta Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of various cells using Casein Kinase II Beta Polyclonal Antibody

Anti-CSNK2B antibody (166-215 aa) (STJ92009)

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STJ92009

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Casein kinase II subunit beta (166-215 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:5000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CSNK2B
Gene ID:	1460
Uniprot ID:	CSK2B_HUMAN
Immunogen Region:	166-215 aa
Specificity:	Casein Kinase II Beta Polyclonal Antibody detects endogenous levels of Casein Kinase II Beta protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human CKII-beta at the amino acid range 166-215

Function	Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling. (Microbial infection) Upon infection with Epstein-Barr virus (EBV), the interaction with viral EBNA1 increases the association of CK2 with PML proteins, which increases PML phosphorylation by CK2, triggering the polyubiquitylation and degradation of PML. Seems to also suppress EBV reactivation by mediating ARK2N and JUN at the Z promoter which inhibits BZLF1 transcrition.
Protein Name	Casein Kinase Ii Subunit Beta Ck Ii Beta Phosvitin Protein G5a
Database Links	Reactome: R-HSA-1483191 Reactome: R-HSA-201688 Reactome: R-HSA-2514853 Reactome: R-HSA-445144 Reactome: R-HSA-6798695 Reactome: R-HSA-6804756 Reactome: R-HSA-6814122 Reactome: R-HSA-8934903 Reactome: R-HSA-8939243 Reactome: R-HSA-8948751 Reactome: R-HSA-9755511
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Casein Kinase Ii Subunit Beta antibody Anti-Ck Ii Beta antibody Anti-Phosvitin antibody Anti-Protein G5a antibody Anti-CSNK2B antibody Anti-CK2N antibody Anti-G5A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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