Anti-CRX antibody (STJA0037891)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human CORD2
General Information
| Short Description | Rabbit monoclonal anti-CRX for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CRX |
| Gene ID | 1406 |
| Uniprot ID | CRX_HUMAN |
| Immunogen | A synthesized peptide derived from human CORD2 |
Additional Info
| Tissue Specificity | Retina. |
| Function | Transcription factor that binds and transactivates the sequence 5'-TAATCCA-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. |
| Protein Name | Cone-Rod Homeobox Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cone-Rod Homeobox Protein antibodyAnti-CRX antibodyAnti-CORD2 antibody |
Information sourced from Uniprot.org