| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CRLS1 (1-110) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CRLS1 |
| Gene ID: |
54675 |
| Uniprot ID: |
CRLS1_HUMAN |
| Immunogen Region: |
1-110 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human CRLS1 (NP_061968.1). |
| Immunogen Sequence: |
MLALRVARGSWGALRGAAWA PGTRPSKRRACWALLPPVPC CLGCLAERWRLRPAALGLRL PGIGQRNHCSGAGKAAPRPA AGAGAAAEAPGGQWGPASTP SLYENPWTIP |
| Tissue Specificity | Highly expressed in tissues such as heart, skeletal muscle and liver. |
| Function | Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. |
| Protein Name | Cardiolipin SynthaseCmp-FormingClsProtein Gcd10 Homolog |
| Database Links | Reactome: R-HSA-1482925Reactome: R-HSA-1483076 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cardiolipin Synthase antibodyAnti-Cmp-Forming antibodyAnti-Cls antibodyAnti-Protein Gcd10 Homolog antibodyAnti-CRLS1 antibodyAnti-C20orf155 antibodyAnti-CLS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
