| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CRLS1 |
| Gene ID: | 54675 |
| Uniprot ID: | CRLS1_HUMAN |
| Immunogen Region: | 1-110 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human CRLS1 (NP_061968.1). |
| Immunogen Sequence: | MLALRVARGSWGALRGAAWA PGTRPSKRRACWALLPPVPC CLGCLAERWRLRPAALGLRL PGIGQRNHCSGAGKAAPRPA AGAGAAAEAPGGQWGPASTP SLYENPWTIP |
| Tissue Specificity | Highly expressed in tissues such as heart, skeletal muscle and liver. |
| Function | Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. |
| Protein Name | Cardiolipin SynthaseCmp-FormingClsProtein Gcd10 Homolog |
| Database Links | Reactome: R-HSA-1482925Reactome: R-HSA-1483076 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cardiolipin Synthase antibodyAnti-Cmp-Forming antibodyAnti-Cls antibodyAnti-Protein Gcd10 Homolog antibodyAnti-CRLS1 antibodyAnti-C20orf155 antibodyAnti-CLS1 antibody |
Information sourced from Uniprot.org