| Host: |
Mouse |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Corticotropin-releasing factor receptor 2 (50-150) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
PTR1205 |
| Conjugation: |
Unconjugated |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CRHR2 |
| Gene ID: |
1395 |
| Uniprot ID: |
CRFR2_HUMAN |
| Immunogen Region: |
50-150 |
| Specificity: |
This antibody detects endogenous levels of CRHR2 at Human, Predict react with Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human CRHR2 AA range: 50-150 |
| Post Translational Modifications | A N-glycosylation site within the signal peptide impedes its proper cleavage and function. |
| Function | G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. |
| Protein Name | Corticotropin-Releasing Factor Receptor 2Crf-R-2Crf-R2Crfr-2Corticotropin-Releasing Hormone Receptor 2Crh-R-2Crh-R2 |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555Reactome: R-HSA-422085 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Corticotropin-Releasing Factor Receptor 2 antibodyAnti-Crf-R-2 antibodyAnti-Crf-R2 antibodyAnti-Crfr-2 antibodyAnti-Corticotropin-Releasing Hormone Receptor 2 antibodyAnti-Crh-R-2 antibodyAnti-Crh-R2 antibodyAnti-CRHR2 antibodyAnti-CRF2R antibodyAnti-CRH2R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
