| Host: |
Rabbit |
| Applications: |
WB/IHC-P/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:5000IHC-P:1:100-1:500IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CRHBP |
| Gene ID: |
1393 |
| Uniprot ID: |
CRHBP_HUMAN |
| Immunogen Region: |
25-322 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-322 of human CRHBP (NP_001873.2). |
| Immunogen Sequence: |
YLELREAADYDPFLLFSANL KRELAGEQPYRRALRCLDML SLQGQFTFTADRPQLHCAAF FISEPEEFITIHYDQVSIDC QGGDFLKVFDGWILKGEKFP SSQDHPLPSAERYIDFCESG LSRRSIRSSQNVAMIFFRVH EPGNGFTLTIKTDPNLFPCN VISQTPNGKFTLVVPHQHRN CSFSIIYPVVIKISDLTLGH VNGLQLKKSSAGCEGIGDFV ELLGGTGLDPSKMTPLADL |
| Function | Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. |
| Protein Name | Corticotropin-Releasing Factor-Binding ProteinCrf-BpCrf-Binding ProteinCorticotropin-Releasing Hormone-Binding ProteinCrh-Bp |
| Database Links | Reactome: R-HSA-373080 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Corticotropin-Releasing Factor-Binding Protein antibodyAnti-Crf-Bp antibodyAnti-Crf-Binding Protein antibodyAnti-Corticotropin-Releasing Hormone-Binding Protein antibodyAnti-Crh-Bp antibodyAnti-CRHBP antibodyAnti-CRFBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and SPK knockout (KO) 293T cells, using [KO Validated] SPK Rabbit polyclonal antibody (STJ11100823) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89759/358235/STJ11100823_1__81500.1713122567.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and SPK knockout (KO) 293T cells, using [KO Validated] SPK Rabbit polyclonal antibody (STJ11100823) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
