| Short Description : | Rabbit polyclonal anti-Cytochrome c oxidase assembly protein COX19 (10-59 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | COX19 |
| Gene ID: | 90639 |
| Uniprot ID: | COX19_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human COX19 at the amino acid range 10-59 |
| Immunogen Region: | 10-59 aa |
| Specificity: | COX19 Polyclonal Antibody detects endogenous levels of COX19 protein. |
| Function | Required for the transduction of an SCO1-dependent redox signal from the mitochondrion to ATP7A to regulate cellular copper homeostasis. May be required for the assembly of mitochondrial cytochrome c oxidase. |
| Protein Name | Cytochrome C Oxidase Assembly Protein Cox19Hcox19 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9864848 |
| Cellular Localisation | CytoplasmCytosolMitochondrion Intermembrane SpaceMitochondrionPartitions Between Mitochondria And The Cytosol In A Copper-Dependent MannerEnriched In The Cytosol When Intracellular Copper Concentrations Are Elevated |
| Alternative Antibody Names | Anti-Cytochrome C Oxidase Assembly Protein Cox19 antibodyAnti-Hcox19 antibodyAnti-COX19 antibody |
Information sourced from Uniprot.org
