Western blot analysis of various lysates, using COQ7 rabbit polyclonal antibody (STJ110079) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-COQ7 antibody (37-217) (STJ110079)

SKU:
STJ110079
£112.50 - £524.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:5000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COQ7
Gene ID: 10229
Uniprot ID: COQ7_HUMAN
Immunogen Region: 37-217
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 37-217 of human COQ7 (NP_057222.2).
Immunogen Sequence: SGMTLDNISRAAVDRIIRVD HAGEYGANRIYAGQMAVLGR TSVGPVIQKMWDQEKDHLKK FNELMVTFRVRPTVLMPLWN VLGFALGAGTALLGKEGAMA CTVAVEESIAHHYNNQIRTL MEEDPEKYEELLQLIKKFRD EELEHHDIGLDHDAELAPAY AVLKSIIQAGCRVAIYLSER L
Tissue Specificity Expressed dominantly in heart and skeletal muscle.
Function Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner. Plays a role in modulating mitochondrial stress responses, acting in the nucleus, perhaps via regulating gene expression, independent of its characterized mitochondrial function in ubiquinone biosynthesis.
Protein Name 5-Demethoxyubiquinone Hydroxylase - Mitochondrial
Dmq Hydroxylase
Timing Protein Clk-1 Homolog
Ubiquinone Biosynthesis Monooxygenase Coq7
Database Links Reactome: R-HSA-2142789
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Matrix Side
Mitochondrion
Nucleus
Chromosome
Alternative Antibody Names Anti-5-Demethoxyubiquinone Hydroxylase - Mitochondrial antibody
Anti-Dmq Hydroxylase antibody
Anti-Timing Protein Clk-1 Homolog antibody
Anti-Ubiquinone Biosynthesis Monooxygenase Coq7 antibody
Anti-COQ7 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0006844 Anti-COQ7 antibody (STJA0006844) Rabbit Polyclonal Human/Mouse/Rat WB
STJ117388 Anti-ULBP2 antibody (26-217) (STJ117388) Rabbit Polyclonal Human/Mouse/Rat WB/IF/ICC/ELISA
STJ23239 Anti-CSH1 antibody (27-217) (STJ23239) Rabbit Polyclonal Human IHC-P/ELISA
STJ71391 Anti-SOX8 antibody (203-217) (STJ71391) Goat Polyclonal Human Pep-ELISA
STJ110095 Anti-HARS2 antibody (217-506) (STJ110095) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ110503 Anti-ARFGAP3 antibody (217-516) (STJ110503) Rabbit Polyclonal Human/Mouse WB/ELISA
STJ23126 Anti-CHIT1 antibody (217-466) (STJ23126) Rabbit Polyclonal Human/Mouse WB/IHC-P/ELISA
STJ72279 Anti-FANCF antibody (217-228) (STJ72279) Goat Polyclonal Human Pep-ELISA/WB-Trf
!