• Western blot analysis of various lysates using COPG1 Rabbit polyclonal antibody (STJ112569) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-COPG1 antibody (555-874) (STJ112569)

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STJ112569

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-COPG1 (555-874) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COPG1
Gene ID: 22820
Uniprot ID: COPG1_HUMAN
Immunogen Region: 555-874
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 555-874 of human COPG1 (NP_057212.1).
Immunogen Sequence: IPGLERALQQYTLEPSEKPF DLKSVPLATAPMAEQRTEST PITAVKQPEKVAATRQEIFQ EQLAAVPEFRGLGPLFKSSP EPVALTESETEYVIRCTKHT FTNHMVFQFDCTNTLNDQTL ENVTVQMEPTEAYEVLCYVP ARSLPYNQPGTCYTLVALPK EDPTAVACTFSCMMKFTVKD CDPTTGETDDEGYEDEYVLE DLEVTVADHIQKVMKLNFEA AWDEVGDEFEKEETFTLST
Function The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins.the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis.
Protein Name Coatomer Subunit Gamma-1
Gamma-1-Coat Protein
Gamma-1-Cop
Database Links Reactome: R-HSA-6807878
Reactome: R-HSA-6811434
Cellular Localisation Cytoplasm
Golgi Apparatus Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasmic Vesicle
Copi-Coated Vesicle Membrane
The Coatomer Is Cytoplasmic Or Polymerized On The Cytoplasmic Side Of The Golgi
As Well As On The Vesicles/Buds Originating From It
Predominantly Located In The Cis-Golgi Apparatus
Alternative Antibody Names Anti-Coatomer Subunit Gamma-1 antibody
Anti-Gamma-1-Coat Protein antibody
Anti-Gamma-1-Cop antibody
Anti-COPG1 antibody
Anti-COPG antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance