| Short Description : | Goat polyclonal antibody anti-Collagen, type VII (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications: | Pep-ELISA/WB |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 250kDa band observed in Rat Testis lysates (calculated MW of 159kDa according to Rat NP_001100328.1). Recommended concentration: 0.1-1.5µg/ml.A customer found this antibody |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | COL7A1 |
| Gene ID: | 1294 |
| Uniprot ID: | CO7A1_HUMAN |
| Accession Number: | NP_000085.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | TVQYSDDPRTEF |
| Specificity: | This product does not work on cryostat sections of Normal Human Skin. |
| Function | Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. |
| Protein Name | Collagen Alpha-1(Vii ChainLong-Chain CollagenLc Collagen |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474244Reactome: R-HSA-1650814Reactome: R-HSA-2022090Reactome: R-HSA-204005Reactome: R-HSA-216083Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-5694530Reactome: R-HSA-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement Membrane |
| Alternative Antibody Names | Anti-Collagen Alpha-1(Vii Chain antibodyAnti-Long-Chain Collagen antibodyAnti-Lc Collagen antibodyAnti-COL7A1 antibody |
Information sourced from Uniprot.org
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