| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CNTNAP2 (ECD) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
CNTNAP2 |
| Gene ID: |
26047 |
| Uniprot ID: |
CNTP2_HUMAN |
| Immunogen Region: |
ECD |
| Specificity: |
Specific for CNTNAP2. |
| Immunogen: |
A synthetic peptide from extracellular domain of human Contactin associated protein like 2 (CNTNAP2) conjugated to blue carrier protein was used as the antigen. |
| Function | Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction. |
| Protein Name | Contactin-Associated Protein-Like 2Cell Recognition Molecule Caspr2 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionAxonCell JunctionParanodal Septate JunctionExpressed In The Juxtaparadonal Region |
| Alternative Antibody Names | Anti-Contactin-Associated Protein-Like 2 antibodyAnti-Cell Recognition Molecule Caspr2 antibodyAnti-CNTNAP2 antibodyAnti-CASPR2 antibodyAnti-KIAA0868 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
