Anti-CNBP antibody (70-170) (STJ117304)

Name: Anti-CNBP antibody (70-170) (STJ117304)
SKU: STJ117304
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ117304

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Short Description	Rabbit polyclonal CNBP (70-170) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CNBP
Gene ID	7555
Uniprot ID	CNBP_HUMAN
Immunogen Region	70-170
Immunogen Sequence	CGRGGHIAKDCKEPKREREQ CCYNCGKPGHLARDCDHADE QKCYSCGEFGHIQKDCTKVK CYRCGETGHVAINCSKTSEV NCYRCGESGHLARECTIEAT A
Specificity	A synthetic peptide corresponding to a sequence within amino acids 70-170 of human CNBP (NP_001120668.1).

Tissue Specificity	Expressed in the liver, kidney, spleen, testis, lung, muscle and adrenal glands.
Post Translational Modifications	Arginine methylation by PRMT1 in the Arg/Gly-rich region impedes RNA binding.
Function	Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression. Has a role as transactivator of the Myc promoter. Binds single-stranded RNA in a sequence-specific manner. Isoform 1: Binds G-rich elements in target mRNA coding sequences. Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs. Isoform 2: Binds to RNA. Isoform 4: Binds to RNA. Isoform 5: Binds to RNA. Isoform 6: Binds to RNA. Isoform 8: Binds to RNA.
Protein Name	Cchc-Type Zinc Finger Nucleic Acid Binding Protein Cellular Nucleic Acid-Binding Protein Cnbp Zinc Finger Protein 9
Database Links	Reactome: R-HSA-9705671
Cellular Localisation	Nucleus Cytoplasm Endoplasmic Reticulum Isoform 1: Cytoplasm Isoform 2: Cytoplasm Isoform 4: Cytoplasm Isoform 5: Cytoplasm Isoform 6: Cytoplasm Isoform 8: Cytoplasm
Alternative Antibody Names	Anti-Cchc-Type Zinc Finger Nucleic Acid Binding Protein antibody Anti-Cellular Nucleic Acid-Binding Protein antibody Anti-Cnbp antibody Anti-Zinc Finger Protein 9 antibody Anti-CNBP antibody Anti-RNF163 antibody Anti-ZNF9 antibody

Information sourced from Uniprot.org