| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CLEC11A (22-323) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CLEC11A |
| Gene ID: |
6320 |
| Uniprot ID: |
CLC11_HUMAN |
| Immunogen Region: |
22-323 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-323 of human CLEC11A (NP_002966.1). |
| Immunogen Sequence: |
ARGAEREWEGGWGGAQEEER EREALMLKHLQEALGLPAGR GDENPAGTVEGKEDWEMEED QGEEEEEEATPTPSSGPSPS PTPEDIVTYILGRLAGLDAG LHQLHVRLHALDTRVVELTQ GLRQLRNAAGDTRDAVQALQ EAQGRAEREHGRLEGCLKGL RLGHKCFLLSRDFEAQAAAQ ARCTARGGSLAQPADRQQME ALTRYLRAALAPYNWPVWLG VHDRRAEGLYLFENGQRVS |
| Tissue Specificity | Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver. |
| Post Translational Modifications | O-glycosylated. Probably sulfated on the O-glycans. |
| Function | Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone. |
| Protein Name | C-Type Lectin Domain Family 11 Member AC-Type Lectin Superfamily Member 3Lymphocyte Secreted C-Type LectinOsteolectinStem Cell Growth FactorP47 |
| Cellular Localisation | CytoplasmSecreted |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 11 Member A antibodyAnti-C-Type Lectin Superfamily Member 3 antibodyAnti-Lymphocyte Secreted C-Type Lectin antibodyAnti-Osteolectin antibodyAnti-Stem Cell Growth Factor antibodyAnti-P47 antibodyAnti-CLEC11A antibodyAnti-CLECSF3 antibodyAnti-LSLCL antibodyAnti-SCGF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and ERCC1 knockout (KO) HeLa cells, using [KO Validated] ERCC1 Rabbit polyclonal antibody (STJ11100039) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89111/357565/STJ11100039_1__56308.1713121691.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and ERCC1 knockout (KO) HeLa cells, using [KO Validated] ERCC1 Rabbit polyclonal antibody (STJ11100039) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.")