| Host: |
Mouse |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Claudin-7 (100-211 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ABT443 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2bk |
| Formulation: |
Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: |
IHC-P 1:200-400WB 500-1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CLDN7 |
| Gene ID: |
1366 |
| Uniprot ID: |
CLD7_HUMAN |
| Immunogen Region: |
100-211 aa |
| Specificity: |
The antibody can specifically recognize human Claudin 7 protein. In western blotting of LnCap cell lysate, the antibody can label a 22 kDa band corresponding to Claudin 7.. The antibody was also Predi |
| Immunogen: |
Synthesized peptide derived from the human Claudin 7 at the amino acid range 100-211 |
| Post Translational Modifications | Phosphorylated. |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space. |
| Protein Name | Claudin-7Cldn-7 |
| Database Links | Reactome: R-HSA-420029 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneCell JunctionTight JunctionCo-Localizes With Epcam At The Basolateral Cell Membrane And Tight Junction |
| Alternative Antibody Names | Anti-Claudin-7 antibodyAnti-Cldn-7 antibodyAnti-CLDN7 antibodyAnti-CEPTRL2 antibodyAnti-CPETRL2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
