| Host: | Mouse |
| Applications: | IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Claudin-7 (100-211 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ABT443 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2bk |
| Formulation: | Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:200-400WB 500-1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CLDN7 |
| Gene ID: | 1366 |
| Uniprot ID: | CLD7_HUMAN |
| Immunogen Region: | 100-211 aa |
| Specificity: | The antibody can specifically recognize human Claudin 7 protein. In western blotting of LnCap cell lysate, the antibody can label a 22 kDa band corresponding to Claudin 7.. The antibody was also Predi |
| Immunogen: | Synthesized peptide derived from the human Claudin 7 at the amino acid range 100-211 |
| Post Translational Modifications | Phosphorylated. |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space. |
| Protein Name | Claudin-7Cldn-7 |
| Database Links | Reactome: R-HSA-420029 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneCell JunctionTight JunctionCo-Localizes With Epcam At The Basolateral Cell Membrane And Tight Junction |
| Alternative Antibody Names | Anti-Claudin-7 antibodyAnti-Cldn-7 antibodyAnti-CLDN7 antibodyAnti-CEPTRL2 antibodyAnti-CPETRL2 antibody |
Information sourced from Uniprot.org