• Human appendix tissue was stained with Anti-Claudin 4 (PT1925) Antibody
  • Whole cell lysates were separated by 12% SDS-PAGE, and the membrane was blotted with anti-Claudin 4 (PT1925) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: LnCapPredicted band size: 22kDaObserved band size: 18kDa
  • Immunohistochemical analysis of paraffin-embedded Colon. 1, Antibody was diluted at 1:200 (4°C overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
  • Immunohistochemical analysis of paraffin-embedded Pancreatic carcinoma. 1, Antibody was diluted at 1:200 (4°C overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-CLDN4 antibody (150-209 aa) [PT1925] (STJ196954)

SKU:
STJ196954

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/IF/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Claudin-4 (150-209 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and Western Blot research applications.
Clonality: Monoclonal
Clone ID: PT1925
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:100-500
WB 1:500-2000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CLDN4
Gene ID: 1364
Uniprot ID: CLD4_HUMAN
Immunogen Region: 150-209 aa
Specificity: This antibody detects endogenous levels of human Claudin 4. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section. The antibody w
Immunogen: Synthesized peptide derived from the human Claudin 4 at the amino acid range 150-209
Function Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Protein Name Claudin-4
Clostridium Perfringens Enterotoxin Receptor
Cpe-R
Cpe-Receptor
Williams-Beuren Syndrome Chromosomal Region 8 Protein
Database Links Reactome: R-HSA-420029
Cellular Localisation Cell Junction
Tight Junction
Cell Membrane
Multi-Pass Membrane Protein
Cldn4 Is Required For Tight Junction Localization In The Kidney
Alternative Antibody Names Anti-Claudin-4 antibody
Anti-Clostridium Perfringens Enterotoxin Receptor antibody
Anti-Cpe-R antibody
Anti-Cpe-Receptor antibody
Anti-Williams-Beuren Syndrome Chromosomal Region 8 Protein antibody
Anti-CLDN4 antibody
Anti-CPER antibody
Anti-CPETR1 antibody
Anti-WBSCR8 antibody

Information sourced from Uniprot.org

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