• Western blot analysis of lysates from A549, COLO, and Jurkat cells, using CHST2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from K562 cells using CHST2 antibody.
  • Western blot analysis of various cells using CHST2 Polyclonal Antibody

Anti-CHST2 antibody (1-50 aa) (STJ92285)

SKU:
STJ92285

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Carbohydrate sulfotransferase 2 (1-50 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CHST2
Gene ID: 9435
Uniprot ID: CHST2_HUMAN
Immunogen Region: 1-50 aa
Specificity: CHST2 Polyclonal Antibody detects endogenous levels of CHST2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CHST2 at the amino acid range 1-50
Post Translational Modifications Glycosylation at Asn-475 is required for catalytic activity.
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.
Protein Name Carbohydrate Sulfotransferase 2
Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 2
Gst-2
N-Acetylglucosamine 6-O-Sulfotransferase 1
Glcnac6st-1
Gn6st-1
Database Links Reactome: R-HSA-2022854
Cellular Localisation Golgi Apparatus
Trans-Golgi Network Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Carbohydrate Sulfotransferase 2 antibody
Anti-Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 2 antibody
Anti-Gst-2 antibody
Anti-N-Acetylglucosamine 6-O-Sulfotransferase 1 antibody
Anti-Glcnac6st-1 antibody
Anti-Gn6st-1 antibody
Anti-CHST2 antibody
Anti-GN6ST antibody

Information sourced from Uniprot.org

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