| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CHRNA4 (29-242) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CHRNA4 |
| Gene ID: |
1137 |
| Uniprot ID: |
ACHA4_HUMAN |
| Immunogen Region: |
29-242 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 29-242 of human ACHA4 (P43681). |
| Immunogen Sequence: |
HVETRAHAEERLLKKLFSGY NKWSRPVANISDVVLVRFGL SIAQLIDVDEKNQMMTTNVW VKQEWHDYKLRWDPADYENV TSIRIPSELIWRPDIVLYNN ADGDFAVTHLTKAHLFHDGR VQWTPPAIYKSSCSIDVTFF PFDQQNCTMKFGSWTYDKAK IDLVNMHSRVDQLDFWESGE WVIVDAVGTYNTRKYECCAE IYPDITYAFVIRRL |
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions. |
| Protein Name | Neuronal Acetylcholine Receptor Subunit Alpha-4 |
| Database Links | Reactome: R-HSA-629587Reactome: R-HSA-629594Reactome: R-HSA-629597 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Neuronal Acetylcholine Receptor Subunit Alpha-4 antibodyAnti-CHRNA4 antibodyAnti-NACRA4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
