Anti-CHRM1 antibody (251-350) (STJ23130)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CHRM1 (251-350) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHRM1 |
| Gene ID | 1128 |
| Uniprot ID | ACM1_HUMAN |
| Immunogen Region | 251-350 |
| Immunogen Sequence | SPETPPGRCCRCCRAPRLLQ AYSWKEEEEEDEGSMESLTS SEGEEPGSEVVIKMPMVDPE AQAPTKQPPRSSPNTVKRPT KKGRDRAGKGQKPRGKEQLA |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 251-350 of human CHRM1 (NP_000729.2). |
Additional Info
| Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. |
| Protein Name | Muscarinic Acetylcholine Receptor M1 |
| Database Links | Reactome: R-HSA-390648Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Muscarinic Acetylcholine Receptor M1 antibodyAnti-CHRM1 antibody |
Information sourced from Uniprot.org