• Western blot analysis of various lysates using CHMP7 Rabbit polyclonal antibody (STJ116572) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-CHMP7 antibody (230-453) (STJ116572)

SKU:
STJ116572

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CHMP7 (230-453) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CHMP7
Gene ID: 91782
Uniprot ID: CHMP7_HUMAN
Immunogen Region: 230-453
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-453 of human CHMP7 (NP_689485.1).
Immunogen Sequence: KVSPVNDVDVGVYQLMQSEQ LLSRKVESLSQEAERCKEEA RRACRAGKKQLALRSLKAKQ RTEKRIEALHAKLDTVQGIL DRIYASQTDQMVFNAYQAGV GALKLSMKDVTVEKAESLVD QIQELCDTQDEVSQTLAGGV TNGLDFDSEELEKELDILLQ DTTKEPLDLPDNPRNRHFTN SVPNPRISDAELEAELEKLS LSEGGLVPSSKSPKRQLEPT LKPL
Function ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope (NE) during late anaphase. Together with SPAST, the ESCRT-III complex promotes NE sealing and mitotic spindle disassembly during late anaphase. Recruited to the reforming NE during anaphase by LEMD2. Plays a role in the endosomal sorting pathway.
Protein Name Charged Multivesicular Body Protein 7
Chromatin-Modifying Protein 7
Database Links Reactome: R-HSA-162588
Reactome: R-HSA-1632852
Reactome: R-HSA-5620971
Reactome: R-HSA-917729
Reactome: R-HSA-9610379
Reactome: R-HSA-9615710
Reactome: R-HSA-9668328
Reactome: R-HSA-9679504
Reactome: R-HSA-9694676
Cellular Localisation Cytoplasm
Nucleus Envelope
Diffused Localization
With Some Punctate Distribution
Especially In The Perinuclear Area
Localizes To The Reforming Nuclear Envelope On Chromatin Disks During Late Anaphase
Alternative Antibody Names Anti-Charged Multivesicular Body Protein 7 antibody
Anti-Chromatin-Modifying Protein 7 antibody
Anti-CHMP7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance