| Short Description : | Rabbit polyclonal CHIT1 (217-466) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHIT1 |
| Gene ID: | 1118 |
| Uniprot ID: | CHIT1_HUMAN |
| Immunogen Region: | 217-466 |
| Immunogen Sequence: | SWEKVTGHNSPLYKRQEESG AAASLNVDAAVQQWLQKGTP ASKLILGMPTYGRSFTLASS SDTRVGAPATGSGTPGPFTK EGGMLAYYEVCSWKGATKQR IQDQKVPYIFRDNQWVGFDD VESFKTKVSYLKQKGLGGAM VWALDLDDFAGFSCNQGRYP LIQTLRQELSLPYLPSGTPE LEVPKPGQPSEPEHGPSPGQ DTFCQGKADGLYPNPRERSS FYSCAAGRLFQQSCPTGLV |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 217-466 of human CHIT1 (NP_003456.1). |
| Tissue Specificity | Detected in spleen. Secreted by cultured macrophages. |
| Function | Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. |
| Protein Name | Chitotriosidase-1Chitinase-1 |
| Database Links | Reactome: R-HSA-189085Reactome: R-HSA-6798695 |
| Cellular Localisation | SecretedLysosomeA Small Proportion Is Lysosomal |
| Alternative Antibody Names | Anti-Chitotriosidase-1 antibodyAnti-Chitinase-1 antibodyAnti-CHIT1 antibody |
Information sourced from Uniprot.org
