| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CHIT1 (217-466) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CHIT1 |
| Gene ID: |
1118 |
| Uniprot ID: |
CHIT1_HUMAN |
| Immunogen Region: |
217-466 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 217-466 of human CHIT1 (NP_003456.1). |
| Immunogen Sequence: |
SWEKVTGHNSPLYKRQEESG AAASLNVDAAVQQWLQKGTP ASKLILGMPTYGRSFTLASS SDTRVGAPATGSGTPGPFTK EGGMLAYYEVCSWKGATKQR IQDQKVPYIFRDNQWVGFDD VESFKTKVSYLKQKGLGGAM VWALDLDDFAGFSCNQGRYP LIQTLRQELSLPYLPSGTPE LEVPKPGQPSEPEHGPSPGQ DTFCQGKADGLYPNPRERSS FYSCAAGRLFQQSCPTGLV |
| Tissue Specificity | Detected in spleen. Secreted by cultured macrophages. |
| Function | Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. |
| Protein Name | Chitotriosidase-1Chitinase-1 |
| Database Links | Reactome: R-HSA-189085Reactome: R-HSA-6798695 |
| Cellular Localisation | SecretedLysosomeA Small Proportion Is Lysosomal |
| Alternative Antibody Names | Anti-Chitotriosidase-1 antibodyAnti-Chitinase-1 antibodyAnti-CHIT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
