| Short Description : | Rabbit polyclonal CHAMP1 (563-812) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHAMP1 |
| Gene ID: | 283489 |
| Uniprot ID: | CHAP1_HUMAN |
| Immunogen Region: | 563-812 |
| Immunogen Sequence: | LPKSALFSESQKAVELGDEL QIDAIDDQKCDILVQEELLA SPKKLLEDTLFPSSKKLKKD NQESSDAELSSSEYIKTDLD AMDIKGQESSSDQEQVDVES IDFSKENKMDMTSPEQSRNV LQFTEEKEAFISEEEIAKYM KRGKGKYYCKICCCRAMKKG AVLHHLVNKHNVHSPYKCTI CGKAFLLESLLKNHVAAHGQ SLLKCPRCNFESNFPRGFKK HLTHCQSRHNEEANKKLME |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 563-812 of human CHAMP1 (NP_115812.1). |
| Post Translational Modifications | Phosphorylated by CDK1. Mitotic phosphorylation is required for the attachment of spindle microtubules to the kinetochore. |
| Function | Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore. |
| Protein Name | Chromosome Alignment-Maintaining Phosphoprotein 1Zinc Finger Protein 828 |
| Database Links | |
| Cellular Localisation | NucleusChromosomeCentromereKinetochoreCytoplasmCytoskeletonSpindle |
| Alternative Antibody Names | Anti-Chromosome Alignment-Maintaining Phosphoprotein 1 antibodyAnti-Zinc Finger Protein 828 antibodyAnti-CHAMP1 antibodyAnti-C13orf8 antibodyAnti-CAMP antibodyAnti-CHAMP antibodyAnti-KIAA1802 antibodyAnti-ZNF828 antibody |
Information sourced from Uniprot.org
