Anti-CHAF1A antibody (100-200) [S3MR] (STJ11102363)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal p150 CAF1 (100-200) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHAF1A |
| Gene ID | 10036 |
| Uniprot ID | CAF1A_HUMAN |
| Immunogen Region | 100-200 |
| Immunogen Sequence | NFLRNRIETSIGQSTVIIDL TEDSNEQPDSLVDHNKLNSE ASPSREAINGQREDTGDQQG LLKAIQNDKLAFPGETLSDI PCKTEEEGVGCGGAGRRGDS Q |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human p150 CAF1 (NP_005474.2). |
Additional Info
| Function | Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA.histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci. |
| Protein Name | Chromatin Assembly Factor 1 Subunit ACaf-1 Subunit AChromatin Assembly Factor I P150 SubunitCaf-I 150 Kda SubunitCaf-I P150Hp150 |
| Database Links | |
| Cellular Localisation | NucleusDna Replication Foci |
| Alternative Antibody Names | Anti-Chromatin Assembly Factor 1 Subunit A antibodyAnti-Caf-1 Subunit A antibodyAnti-Chromatin Assembly Factor I P150 Subunit antibodyAnti-Caf-I 150 Kda Subunit antibodyAnti-Caf-I P150 antibodyAnti-Hp150 antibodyAnti-CHAF1A antibodyAnti-CAF antibodyAnti-CAF1P150 antibody |
Information sourced from Uniprot.org