Anti-CES2 antibody (Internal) (STJ92239)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the Internal region of human CES2.
General Information
| Short Description | Rabbit polyclonal anti-Cocaine esterase (Internal) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CES2 |
| Gene ID | 8824 |
| Uniprot ID | EST2_HUMAN |
| Immunogen | Synthesized peptide derived from the Internal region of human CES2. |
| Immunogen Region | Internal |
| Specificity | CES2 Polyclonal Antibody detects endogenous levels of CES2 protein. |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins. |
| Protein Name | Cocaine EsteraseCarboxylesterase 2Ce-2Hce-2Methylumbelliferyl-Acetate Deacetylase 2 |
| Database Links | Reactome: R-HSA-211945Reactome: R-HSA-9749641 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Cocaine Esterase antibodyAnti-Carboxylesterase 2 antibodyAnti-Ce-2 antibodyAnti-Hce-2 antibodyAnti-Methylumbelliferyl-Acetate Deacetylase 2 antibodyAnti-CES2 antibodyAnti-ICE antibody |
Information sourced from Uniprot.org