| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ceramide transfer protein is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CERT1 |
| Gene ID: |
10087 |
| Uniprot ID: |
CERT_HUMAN |
| Specificity: |
This antibody detects endogenous levels of COL4A3BP at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human COL4A3BP |
| Post Translational Modifications | Phosphorylation on Ser-132 decreases the affinity toward phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity. Inactivated by hyperphosphorylation of serine residues by CSNK1G2/CK1 that triggers dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. |
| Function | Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner. |
| Protein Name | Ceramide Transfer ProteinHcertCollagen Type Iv Alpha-3-Binding ProteinGoodpasture Antigen-Binding ProteinGpbpStart Domain-Containing Protein 11Stard11Star-Related Lipid Transfer Protein 11 |
| Database Links | Reactome: R-HSA-1660661 Q9Y5P4-2 |
| Cellular Localisation | CytoplasmGolgi ApparatusEndoplasmic ReticulumPreferentially Localized To The Golgi Apparatus |
| Alternative Antibody Names | Anti-Ceramide Transfer Protein antibodyAnti-Hcert antibodyAnti-Collagen Type Iv Alpha-3-Binding Protein antibodyAnti-Goodpasture Antigen-Binding Protein antibodyAnti-Gpbp antibodyAnti-Start Domain-Containing Protein 11 antibodyAnti-Stard11 antibodyAnti-Star-Related Lipid Transfer Protein 11 antibodyAnti-CERT1 antibodyAnti-CERT antibodyAnti-COL4A3BP antibodyAnti-STARD11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
