| Post Translational Modifications | Phosphorylation on Ser-132 decreases the affinity toward phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity. Inactivated by hyperphosphorylation of serine residues by CSNK1G2/CK1 that triggers dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. |
| Function | Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner. |
| Protein Name | Ceramide Transfer ProteinHcertCollagen Type Iv Alpha-3-Binding ProteinGoodpasture Antigen-Binding ProteinGpbpStart Domain-Containing Protein 11Stard11Star-Related Lipid Transfer Protein 11 |
| Database Links | Reactome: R-HSA-1660661 Q9Y5P4-2 |
| Cellular Localisation | CytoplasmGolgi ApparatusEndoplasmic ReticulumPreferentially Localized To The Golgi Apparatus |
| Alternative Antibody Names | Anti-Ceramide Transfer Protein antibodyAnti-Hcert antibodyAnti-Collagen Type Iv Alpha-3-Binding Protein antibodyAnti-Goodpasture Antigen-Binding Protein antibodyAnti-Gpbp antibodyAnti-Start Domain-Containing Protein 11 antibodyAnti-Stard11 antibodyAnti-Star-Related Lipid Transfer Protein 11 antibodyAnti-CERT1 antibodyAnti-CERT antibodyAnti-COL4A3BP antibodyAnti-STARD11 antibody |
Information sourced from Uniprot.org
