• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CEP350 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-CEP350 antibody (671-720 aa) (STJ92225)

SKU:
STJ92225

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Centrosome-associated protein 350 (671-720 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CEP350
Gene ID: 9857
Uniprot ID: CE350_HUMAN
Immunogen Region: 671-720 aa
Specificity: CEP350 Polyclonal Antibody detects endogenous levels of CEP350 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CEP35 at the amino acid range 671-720
Post Translational Modifications Phosphorylated during mitosis.
Function Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation.
Protein Name Centrosome-Associated Protein 350
Cep350
Centrosome-Associated Protein Of 350 Kda
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Spindle
Nucleus
Centriole
Cilium Basal Body
Associated With Mitotic Spindles
Nuclear
In Discrete Foci
Associated With Intermediate Filaments
Also Present In The Pericentrosomal Area
Localizes On Both Mother And Daughter Centrioles
Localizes To An Axial Position On The Mother Centriole
Localizes To The Distal End Of The Centriole On The Subdistal Appendage Region
Alternative Antibody Names Anti-Centrosome-Associated Protein 350 antibody
Anti-Cep350 antibody
Anti-Centrosome-Associated Protein Of 350 Kda antibody
Anti-CEP350 antibody
Anti-CAP350 antibody
Anti-KIAA0480 antibody
Anti-GM133 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance