| Function | Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. |
| Protein Name | Centromere Protein CCenp-CCentromere Autoantigen CCentromere Protein C 1Cenp-C 1Interphase Centromere Complex Protein 7 |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-606279Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | NucleusChromosomeCentromereKinetochoreLocalizes Exclusively In The Kinetochore Domain Of Centromeres |
| Alternative Antibody Names | Anti-Centromere Protein C antibodyAnti-Cenp-C antibodyAnti-Centromere Autoantigen C antibodyAnti-Centromere Protein C 1 antibodyAnti-Cenp-C 1 antibodyAnti-Interphase Centromere Complex Protein 7 antibodyAnti-CENPC antibodyAnti-CENPC1 antibodyAnti-ICEN7 antibody |
Information sourced from Uniprot.org
