Anti-CDH11 antibody (120-796) (STJ110409)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CDH11 (120-796) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDH11 |
| Gene ID | 1009 |
| Uniprot ID | CAD11_HUMAN |
| Immunogen Region | 120-796 |
| Immunogen Sequence | ERAQYTLMAQAVDRDTNRPL EPPSEFIVKVQDINDNPPEF LHETYHANVPERSNVGTSVI QVTASDADDPTYGNSAKLVY SILEGQPYFSVEAQTGIIRT ALPNMDREAKEEYHVVIQAK DMGGHMGGLSGTTKVTITLT DVNDNPPKFPQSVYQMSVSE AAVPGEEVGRVKAKDPDIGE NGLVTYNIVDGDGMESFEIT TDYETQEGVIKLKKPVDFET KRAYSLKVEAANVHIDPKF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human CDH11 (NP_001788.2). |
Additional Info
| Tissue Specificity | Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. In the embryo from 67 to 72 days of gestation, detected at high levels in facial mesenchyme including the central palatal mesenchyme, dental mesenchyme, the eye and optic muscle, and the tongue (at protein level). |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. Required for proper focal adhesion assembly. Involved in the regulation of cell migration. |
| Protein Name | Cadherin-11Osf-4Osteoblast CadherinOb-Cadherin |
| Database Links | Reactome: R-HSA-418990Reactome: R-HSA-9759811Reactome: R-HSA-9762292Reactome: R-HSA-9833576 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-11 antibodyAnti-Osf-4 antibodyAnti-Osteoblast Cadherin antibodyAnti-Ob-Cadherin antibodyAnti-CDH11 antibody |
Information sourced from Uniprot.org