| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Sororin is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDCA5 |
| Gene ID: |
113130 |
| Uniprot ID: |
CDCA5_HUMAN |
| Specificity: |
This antibody detects endogenous levels of CDCA5 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human CDCA5 |
| Function | Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair. |
| Protein Name | SororinCell Division Cycle-Associated Protein 5P35 |
| Database Links | Reactome: R-HSA-2467813Reactome: R-HSA-2468052Reactome: R-HSA-2500257 |
| Cellular Localisation | NucleusChromosomeCytoplasmAssociates With Nuclear Chromatin From S Phase Until Metaphase And Is Released In The Cytoplasm Upon Nuclear Envelope Breakdown |
| Alternative Antibody Names | Anti-Sororin antibodyAnti-Cell Division Cycle-Associated Protein 5 antibodyAnti-P35 antibodyAnti-CDCA5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
