Anti-CDC40 antibody (1-100) [S9MR] (STJ11103139)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal CDC40 (1-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S9MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDC40 |
| Gene ID | 51362 |
| Uniprot ID | PRP17_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MSAAIAALAASYGSGSGSES DSDSESSRCPLPAADSLMHL TKSPSSKPSLAVAVDSAPEV AVKEDLETGVHLDPAVKEVQ YNPTYETMFAPEFGPENPFR |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDC40 (O60508). |
Additional Info
| Post Translational Modifications | Undergoes isomerization of the peptide bond between Gly-94 and Pro-95. The reaction is catalyzed by PPIL1. |
| Function | Required for pre-mRNA splicing as component of the activated spliceosome. Plays an important role in embryonic brain development.this function does not require proline isomerization. |
| Protein Name | Pre-Mrna-Processing Factor 17Cell Division Cycle 40 HomologEh-Binding Protein 3Ehb3Prp17 HomologHprp17 |
| Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72187Reactome: R-HSA-73856 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-Pre-Mrna-Processing Factor 17 antibodyAnti-Cell Division Cycle 40 Homolog antibodyAnti-Eh-Binding Protein 3 antibodyAnti-Ehb3 antibodyAnti-Prp17 Homolog antibodyAnti-Hprp17 antibodyAnti-CDC40 antibodyAnti-EHB3 antibodyAnti-PRP17 antibodyAnti-PRPF17 antibody |
Information sourced from Uniprot.org