| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S9MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDC40 |
| Gene ID: | 51362 |
| Uniprot ID: | PRP17_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDC40 (O60508). |
| Immunogen Sequence: | MSAAIAALAASYGSGSGSES DSDSESSRCPLPAADSLMHL TKSPSSKPSLAVAVDSAPEV AVKEDLETGVHLDPAVKEVQ YNPTYETMFAPEFGPENPFR |
| Post Translational Modifications | Undergoes isomerization of the peptide bond between Gly-94 and Pro-95. The reaction is catalyzed by PPIL1. |
| Function | Required for pre-mRNA splicing as component of the activated spliceosome. Plays an important role in embryonic brain development.this function does not require proline isomerization. |
| Protein Name | Pre-Mrna-Processing Factor 17Cell Division Cycle 40 HomologEh-Binding Protein 3Ehb3Prp17 HomologHprp17 |
| Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72187Reactome: R-HSA-73856 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-Pre-Mrna-Processing Factor 17 antibodyAnti-Cell Division Cycle 40 Homolog antibodyAnti-Eh-Binding Protein 3 antibodyAnti-Ehb3 antibodyAnti-Prp17 Homolog antibodyAnti-Hprp17 antibodyAnti-CDC40 antibodyAnti-EHB3 antibodyAnti-PRP17 antibodyAnti-PRPF17 antibody |
Information sourced from Uniprot.org
![Immunoprecipitation analysis of 300 Mu g extracts from 293T cells using 3 Mu g [KO Validated] ATG5 Rabbit monoclonal antibody (STJ11101759). Western blot was performed from the immunoprecipitate using [KO Validated] ATG5 Rabbit monoclonal antibody (STJ11101759) at a dilution of 1:1000.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/90674/360687/STJ11101759_1__34437.1713125386.jpg?c=1 "Immunoprecipitation analysis of 300 Mu g extracts from 293T cells using 3 Mu g [KO Validated] ATG5 Rabbit monoclonal antibody (STJ11101759). Western blot was performed from the immunoprecipitate using [KO Validated] ATG5 Rabbit monoclonal antibody (STJ11101759) at a dilution of 1:1000.")
