• Western blot analysis of various lysates using CDC37 Rabbit polyclonal antibody (STJ23029) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-CDC37 antibody (1-160) (STJ23029)

SKU:
STJ23029

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Host: Rabbit
Applications: WB/IP
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CDC37 (1-160) is suitable for use in Western Blot and Immunoprecipitation research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:1000
IP 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDC37
Gene ID: 11140
Uniprot ID: CDC37_HUMAN
Immunogen Region: 1-160
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human CDC37 (NP_008996.1).
Immunogen Sequence: MVDYSVWDHIEVSDDEDETH PNIDTASLFRWRHQARVERM EQFQKEKEELDRGCRECKRK VAECQRKLKELEVAEGGKAE LERLQAEAQQLRKEERSWEQ KLEEMRKKEKSMPWNVDTLS KDGFSKSMVNTKPEKTEEDS EEVREQKHKTFVEKYEKQIK
Post Translational Modifications Constitutively sumoylated by UBE2I.
Function Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. Inhibits HSP90AA1 ATPase activity.
Protein Name Hsp90 Co-Chaperone Cdc37
Hsp90 Chaperone Protein Kinase-Targeting Subunit
P50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed
Database Links Reactome: R-HSA-1227986
Reactome: R-HSA-1236382
Reactome: R-HSA-5637810
Reactome: R-HSA-5675482
Reactome: R-HSA-8863795
Reactome: R-HSA-9013418
Reactome: R-HSA-9634285
Reactome: R-HSA-9652282
Reactome: R-HSA-9664565
Reactome: R-HSA-9665233
Reactome: R-HSA-9665244
Reactome: R-HSA-9665245
Reactome: R-HSA-9665246
Reactome: R-HSA-9665247
Reactome: R-HSA-9665249
Reactome: R-HSA-9665250
Reactome: R-HSA-9665251
Reactome: R-HSA-9665348
Reactome: R-HSA-9665686
Reactome: R-HSA-9665737
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Hsp90 Co-Chaperone Cdc37 antibody
Anti-Hsp90 Chaperone Protein Kinase-Targeting Subunit antibody
Anti-P50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed antibody
Anti-CDC37 antibody
Anti-CDC37A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance