| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CD70 (47-126) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CD70 |
| Gene ID: |
970 |
| Uniprot ID: |
CD70_HUMAN |
| Immunogen Region: |
47-126 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 47-126 of human CD70 (NP_001243.1). |
| Immunogen Sequence: |
QLPLESLGWDVAELQLNHTG PQQDPRLYWQGGPALGRSFL HGPELDKGQLRIHRDGIYMV HIQVTLAICSSTTASRHHPT |
| Function | Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. |
| Protein Name | Cd70 AntigenCd27 LigandCd27-LTumor Necrosis Factor Ligand Superfamily Member 7Cd Antigen Cd70 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Cd70 Antigen antibodyAnti-Cd27 Ligand antibodyAnti-Cd27-L antibodyAnti-Tumor Necrosis Factor Ligand Superfamily Member 7 antibodyAnti-Cd Antigen Cd70 antibodyAnti-CD70 antibodyAnti-CD27L antibodyAnti-CD27LG antibodyAnti-TNFSF7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
