Anti-CD68 antibody [SRM14661] (STJ11109391)

Name: Anti-CD68 antibody [SRM14661] (STJ11109391)
SKU: STJ11109391
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.

STJ11109391

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Short Description	Rabbit monoclonal CD68 antibody for use in WB, IF, ICC, FC and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/FC/ELISA
Host	Rabbit
Reactivity	Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	SRM14661
Isotype	IgG
Conjugation	Unconjugated
Purification	Affinity purification
Dilution Range	WB, 1:500-1:2000 IF/ICC, 1:50-1:200 FC, 1:500-1:1000 ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	Cd68
Gene ID	12514
Uniprot ID	CD68_MOUSE
Immunogen	Recombinant protein (or fragment).This information is considered to be commercially sensitive.

Tissue Specificity	Expressed in tissue macrophages and to a lesser extent in dendritic cells.
Post Translational Modifications	N- and O-glycosylated.
Function	Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Protein Name	Macrosialin Cd Antigen Cd68
Database Links	Reactome: R-MMU-6798695
Cellular Localisation	Isoform Long: Endosome Membrane Single-Pass Type I Membrane Protein Lysosome Membrane Isoform Short: Cell Membrane
Alternative Antibody Names	Anti-Macrosialin antibody Anti-Cd Antigen Cd68 antibody Anti-Cd68 antibody

Information sourced from Uniprot.org