![Anti-CD66c/CEACAM6 nanobody [SAA1208] (STJN000214)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200827/413009/STJN000214-SDS-PAGE-1__33936.1749232527.jpg?c=1 "Anti-CD66c/CEACAM6 nanobody [SAA1208] (STJN000214)")
![Anti-CD66c/CEACAM6 nanobody [SAA1208] (STJN000214)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200827/413009/STJN000214-SDS-PAGE-1__33936.1749232527.jpg?c=1 "Anti-CD66c/CEACAM6 nanobody [SAA1208] (STJN000214)")
Anti-CD66c/CEACAM6 nanobody [SAA1208] (STJN000214)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Cell Adhesion Molecule Ceacam6 is suitable for use in ELISA, Flow Cytometry, Immunofluorescence and Western Blot research applications. |
| Applications | ELISA/FC/IF/WB |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1208 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CEACAM6 |
| Gene ID | 4680 |
| Uniprot ID | CEAM6_HUMAN |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role in cell migration and cell adhesion to endothelial cells. |
| Protein Name | Cell Adhesion Molecule Ceacam6Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6Cea Cell Adhesion Molecule 6Non-Specific Crossreacting AntigenNormal Cross-Reacting AntigenCd Antigen Cd66c |
| Database Links | Reactome: R-HSA-1566977Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorApical Cell MembraneCell SurfaceLocalized To The Apical Glycocalyx Surface |
| Alternative Nanobody Names | Anti-Cell Adhesion Molecule Ceacam6 nanobodyAnti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 nanobodyAnti-Cea Cell Adhesion Molecule 6 nanobodyAnti-Non-Specific Crossreacting Antigen nanobodyAnti-Normal Cross-Reacting Antigen nanobodyAnti-Cd Antigen Cd66c nanobodyAnti-CEACAM6 nanobodyAnti-NCA nanobody |
Information sourced from Uniprot.org