| Short Description : | Mouse monoclonal anti-CD51 for use in IF, IP, FC and IHC-F in Human and Chicken samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IF/IP/FC/IHC-F |
| Host: | Mouse |
| Reactivity: | Human/Chicken |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 23C6 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Concentration: | 1.0 mg/mL |
| Dilution Range: | FC 1:40-1:80 |
| Formulation: | PBS with 0.09% sodium azide |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | Osteoclasts from osteoclastomas. |
| Background | Mouse anti Human CD51/CD61 antibody, clone 23C6 recognizes the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronectin at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Mouse anti Human CD51/CD61 antibody, clone 23C6 reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets. |
Information sourced from Uniprot.org