Host: |
Mouse |
Applications: |
IHC/IF |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-CD38 is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Monoclonal |
Clone ID: |
SM5180 |
Conjugation: |
Unconjugated |
Formulation: |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Dilution Range: |
IHC/IF (H) 1:200-1:500 |
Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Gene Symbol: |
CD38 |
Gene ID: |
952 |
Uniprot ID: |
CD38_HUMAN |
Immunogen: |
Synthesized peptide derived from human CD38 |
Function | Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity. |
Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 12'-Phospho-Adp-Ribosyl Cyclase2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase2'-Phospho-Cyclic-Adp-Ribose TransferaseAdp-Ribosyl Cyclase 1Adprc 1Cyclic Adp-Ribose Hydrolase 1Cadpr Hydrolase 1T10Cd Antigen Cd38 |
Database Links | Reactome: R-HSA-196807 |
Cellular Localisation | Cell SurfaceMembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 antibodyAnti-2'-Phospho-Adp-Ribosyl Cyclase antibodyAnti-2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase antibodyAnti-2'-Phospho-Cyclic-Adp-Ribose Transferase antibodyAnti-Adp-Ribosyl Cyclase 1 antibodyAnti-Adprc 1 antibodyAnti-Cyclic Adp-Ribose Hydrolase 1 antibodyAnti-Cadpr Hydrolase 1 antibodyAnti-T10 antibodyAnti-Cd Antigen Cd38 antibodyAnti-CD38 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance