Anti-CD300 antibody [MEM-260] (STJ16100827)

Anti-CD300 antibody [MEM-260] (STJ16100827)

SKU:
STJ16100827-01
£457.50
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-CD300 is suitable for use in Flow Cytometry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : MEM-260
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration: 1 mg/mL
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: HPB human acute lymphoid leukemia cell line
Background CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.

Information sourced from Uniprot.org

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