Anti-CD30 antibody [Ber‐H2] (STJ180051)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenCo cell line established from a patient with Hodgkin's disease of T-cell lineage
STJ180051
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General Information

Short DescriptionMouse monoclonal CD30 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDBer‐H2
IsotypeIgG1k
ConjugationUnconjugated
PurificationAffinity purified
Dilution Range1:100‐200
FormulationTris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Storage InstructionStore at 2‐8Β°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24Β°C, 3 months at 2‐8Β°C, 6months at ‐20Β°C.

Target Information

Gene SymbolTNFRSF8
Gene ID943
Uniprot IDTNR8_HUMAN
ImmunogenCo cell line established from a patient with Hodgkin's disease of T-cell lineage
SpecificityPositive control: Hodgkin lymphoma or anaplastic large cell lymphoma

Additional Info

Tissue Specificity Isoform 2: Detected in alveolar macrophages (at protein level).
Post Translational Modifications Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated.
Function Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 8
Cd30l Receptor
Ki-1 Antigen
Lymphocyte Activation Antigen Cd30
Cd Antigen Cd30
Database Links Reactome: R-HSA-5669034
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Cytoplasm
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 8 antibody
Anti-Cd30l Receptor antibody
Anti-Ki-1 Antigen antibody
Anti-Lymphocyte Activation Antigen Cd30 antibody
Anti-Cd Antigen Cd30 antibody
Anti-TNFRSF8 antibody
Anti-CD30 antibody
Anti-D1S166E antibody

Information sourced from Uniprot.org

Citations

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