Anti-CD29 antibody [4B7R] (STJ16101910)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenOccular melanoma cell line V+B2
General Information
| Short Description | Mouse monoclonal anti-CD29 for use in FC, IF, IP and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IP/IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 4B7R |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Formulation | PBS with <0.1% sodium azide |
| Storage Instruction | Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
Target Information
| Immunogen | Occular melanoma cell line V+B2 |
Additional Info
| Background | Mouse anti Human CD29 monoclonal antibody, clone 4B7R recognizes the human integrin beta 1 subunit, also known as CD29, a ~130 kDa (red) 115 kDa (non-red) single pass type I transmembrane glycoprotein expressed by most leucocytes and mesenchymal stem cells.Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Surface expression of CD29 on human natural killer cells can be reduced by pretreatment with the glutathioneS-transferase inhibitor diethyl maleate (Horvath-Arcidiacono et al. 2003) |
Information sourced from Uniprot.org