• Western blot analysis of lysate from 293 cells, using CD276 Antibody.
  • Immunohistochemical analysis of paraffin-embedded mouse-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded mouse-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Western blot analysis of 293 cells using CD276 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-CD276 antibody (271-320 aa) (STJ96650)

SKU:
STJ96650

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CD276 antigen (271-320 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD276
Gene ID: 80381
Uniprot ID: CD276_HUMAN
Immunogen Region: 271-320 aa
Specificity: CD276 Polyclonal Antibody detects endogenous levels of CD276 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD276 at the amino acid range 271-320
Function May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Protein Name Cd276 Antigen
4ig-B7-H3
B7 Homolog 3
B7-H3
Costimulatory Molecule
Cd Antigen Cd276
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Cd276 Antigen antibody
Anti-4ig-B7-H3 antibody
Anti-B7 Homolog 3 antibody
Anti-B7-H3 antibody
Anti-Costimulatory Molecule antibody
Anti-Cd Antigen Cd276 antibody
Anti-CD276 antibody
Anti-B7H3 antibody
Anti-PSEC0249 antibody
Anti-UNQ309 antibody
Anti-PRO352 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance