Anti-CD24 antibody [SN3] (STJ16103241)

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STJ16103241-0.1
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Short Description :Mouse monoclonal anti-CD24 for use in FC, IHC-F and MC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC/IHC-F/MC
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SN3
Isotype:IgG1
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Purified by protein-A affinity chromatography.
Formulation:Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Gene Symbol:CD24
Gene ID:100133941
Uniprot ID:CD24_HUMAN
Immunogen:Glycoproteins purified from human NALM-1 cell line.
Post Translational Modifications Extensively O-glycosylated.
Function May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Protein Name Signal Transducer Cd24
Small Cell Lung Carcinoma Cluster 4 Antigen
Cd Antigen Cd24
Database Links Reactome: R-HSA-373760
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Signal Transducer Cd24 antibody
Anti-Small Cell Lung Carcinoma Cluster 4 Antigen antibody
Anti-Cd Antigen Cd24 antibody
Anti-CD24 antibody
Anti-CD24A antibody

Information sourced from Uniprot.org