Anti-CD218a/IL18R1 antibody [1G12] {PE} (STJA0031487)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationPE
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal Interleukin-18 Receptor 1 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1G12 |
| Isotype | IgG1k |
| Conjugation | PE |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | IL18R1 |
| Gene ID | 8809 |
| Uniprot ID | IL18R_HUMAN |
Additional Info
| Post Translational Modifications | N-glycosylated. N-linked glycosyl chains contribute to ligand recognition and intra-receptor interactions required for formation of an active ternary receptor complex. |
| Function | Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3. |
| Protein Name | Interleukin-18 Receptor 1Il-18r-1Il-18r1Cd218 Antigen-Like Family Member ACdw218aIl1 Receptor-Related ProteinIl-1rrpIl1r-RpInterleukin-18 Receptor AlphaIl-18r-AlphaIl-18ralphaCd Antigen Cd218a |
| Database Links | Reactome: R-HSA-9008059Reactome: R-HSA-9012546 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-18 Receptor 1 antibodyAnti-Il-18r-1 antibodyAnti-Il-18r1 antibodyAnti-Cd218 Antigen-Like Family Member A antibodyAnti-Cdw218a antibodyAnti-Il1 Receptor-Related Protein antibodyAnti-Il-1rrp antibodyAnti-Il1r-Rp antibodyAnti-Interleukin-18 Receptor Alpha antibodyAnti-Il-18r-Alpha antibodyAnti-Il-18ralpha antibodyAnti-Cd Antigen Cd218a antibodyAnti-IL18R1 antibodyAnti-IL1RRP antibody |
Information sourced from Uniprot.org