| Short Description : | Rabbit polyclonal anti-Cell surface glycoprotein CD200 receptor 1 (241-290 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD200R1 |
| Gene ID: | 131450 |
| Uniprot ID: | MO2R1_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human MOX2R at the amino acid range 241-290 |
| Immunogen Region: | 241-290 aa |
| Specificity: | OX2R Polyclonal Antibody detects endogenous levels of OX2R protein. |
| Function | Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. |
| Protein Name | Cell Surface Glycoprotein Cd200 Receptor 1Cd200 Cell Surface Glycoprotein ReceptorCell Surface Glycoprotein Ox2 Receptor 1 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 4: Cell MembraneIsoform 2: SecretedIsoform 3: Secreted |
| Alternative Antibody Names | Anti-Cell Surface Glycoprotein Cd200 Receptor 1 antibodyAnti-Cd200 Cell Surface Glycoprotein Receptor antibodyAnti-Cell Surface Glycoprotein Ox2 Receptor 1 antibodyAnti-CD200R1 antibodyAnti-CD200R antibodyAnti-CRTR2 antibodyAnti-MOX2R antibodyAnti-OX2R antibodyAnti-UNQ2522 antibodyAnti-PRO6015 antibody |
Information sourced from Uniprot.org
